Scientists are working on COVID vaccines provided by nasal sprays that can prevent the coronavirus
from invading the body's most common entry point, the mucous membranes of the nose and throat.
The Guardian reports that more than a dozen clinical trials with nasal spray are underway.
USA Today reports that Vietnam, Thailand, Brazil, and Mexico have already begun developing nasal vaccines in hopes of success in clinical trials.
USA Today reports that a nasal vaccine could potentially be used as a booster in the United States but could be widely used in less developed parts of the world where injectable vaccines are not common. Although injectable vaccines help protect the body from serious illness, nasal vaccines can prevent the virus from entering the body first. The effectiveness of the injectable vaccine decreases over time, and different forms of COVID can be avoided with the vaccine, as evidenced by a large number of Omekron cases.
If you think of your body as a castle, an internal vaccination is really protecting the interior of your castle, so once the invaders arrive, the exception is to seize their throne. Protects against, "said Sean Liu, MD, medical director of Cowed Clinical. The trials unit at the Icahn School of Medicine in Mount Sinai, New York City, told The Guardian.
But if you train your immune system to work on the fort's gates, the invaders will not only have difficulty getting inside but will also have difficulty spreading inside."
The nasal vaccine can be more easily prepared and distributed because it is stored in a regular refrigerator instead of extremely cold temperatures such as the Moderna and Pfizer mRNA vaccines. People who do not like needles can get the nasal vaccine.
"And its production will be very cheap," USA Today said. Peter Palace, who is also working on a nasal vaccine at the Ichan School of Medicine, said nasal sprays can be prepared for about 30 cents, compared to $ 30 for a Moderna or Pfizer dose.
Scientists are facing many challenges in their research, especially in measuring the strength of the immune response to the nasal vaccine.
Different techniques are being used to make nasal sprays. At the Ichan School of Medicine, they are developing vaccines in eggs, similar to the flu vaccine. Cincinnati Children's Hospital in Ohio is trying canine flu, USA Today said. The Guardian reports that the nasal version of the Oxford / AstraZeneca vaccine is based on a weak adenovirus.
In January 2021, researchers at the University of Lancaster in England and the Texas Biomedical Research Institute in San Antonio reported that mice receiving two doses of the nasal vaccine had antibody and T cell reactions that suppressed SARS-CoV-2. Were strong enough for
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